Increased Intraepithelial Vα24 Invariant NKT Cells in the Celiac Duodenum

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Increased Intraepithelial Vα24 Invariant NKT Cells in the Celiac Duodenum

Celiac Disease (CD) is an interferon (IFN)γ-mediated duodenal hypersensitivity to wheat gluten occurring in genetically predisposed individuals. Gluten-free diet (GFD) leads to a complete remission of the disease. Vα24-restricted invariant NKT (iNKT) cells are important to maintain immune homeostasis in the gut mucosa because of their unique capacity to rapidly produce large quantities of both ...

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ژورنال

عنوان ژورنال: Nutrients

سال: 2015

ISSN: 2072-6643

DOI: 10.3390/nu7115444